Multiple breath washout quality control in the clinical setting
نویسندگان
چکیده
منابع مشابه
Equipment for multiple breath washout.
5 Demeo DL, Campbell EJ, Barker AF, et al. IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. We read with interest the article ''Paediatrics in Berlin'' [1] in a recent issue of the European Respiratory Journal, which sum-marised the paediatric topics of the European Respiratory Society's Annual Congress in Berlin. In this article, inert gas mul...
متن کاملA Systematic Approach to Multiple Breath Nitrogen Washout Test Quality
BACKGROUND Accurate estimates of multiple breath washout (MBW) outcomes require correct operation of the device, appropriate distraction of the subject to ensure they breathe in a manner representative of their relaxed tidal breathing pattern, and appropriate interpretation of the acquired data. Based on available recommendations for an acceptable MBW test, we aimed to develop a protocol to sys...
متن کاملMultiple-breath washout measurements can be significantly shortened in children.
Multiple-breath washout (MBW)-derived lung clearance index (LCI) is a sensitive measure of ventilation inhomogeneity in patients with cystic fibrosis (CF), but LCI measurement is time consuming. We systematically assessed ways to shorten LCI measurements. In 68 school-aged children (44 with mild CF lung disease) three standard nitrogen (N2) MBWs were applied. We assessed repeatability and diagn...
متن کاملCorrecting for tissue nitrogen excretion in multiple breath washout measurements
Nitrogen excreted from body tissues impacts the calculation of multiple breath nitrogen washout (MBWN2) outcomes. The aim of this study was to determine the effect of tissue N2 on MBWN2 outcomes in both healthy subjects and patients with CF and to assess whether it is possible to correct for tissue N2. The contribution of tissue N2 to MBWN2 outcomes was estimated by comparing MBWN2-derived func...
متن کاملMultiple breath washout analysis in infants: quality assessment and recommendations for improvement.
Infant multiple breath washout (MBW) testing serves as a primary outcome in clinical studies. However, it is still unknown whether current software algorithms allow between-centre comparisons. In this study of healthy infants, we quantified MBW measurement errors and tried to improve data quality by simply changing software settings. We analyzed best quality MBW measurements performed with an u...
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ژورنال
عنوان ژورنال: Pediatric Pulmonology
سال: 2020
ISSN: 8755-6863,1099-0496
DOI: 10.1002/ppul.25119